The Effect of Blackberry Extract on the Total Antioxidant Capacity and Lipid Peroxidation after Acute Resistance Exercise in Obese Men

Document Type : Research Paper



Introduction: Overweight and obesity are major risk factors for cardiovascular morbidity and mortality, that is associated with increased oxidative stress statues. Moreover, despite of many studies that indicated regular exercise training is associated with numerous health benefits, it has been shown that acute exercise might give rise to increased oxidative stress. Therefore, natural supplementation might attenuate oxidative stress in exercise. The present study is conducted to assess the effect of blackberry extract on the total antioxidant capacity and lipid peroxidation after acute resistance exercise in obese men.
Materials and Methods: In a randomized double-blind design, twenty obese men (BMIS 30) were assigned into one of two placebo (n = 10) and supplement (n = 10) groups. Supplement group received 100 mg blackberry daily for seven days while other group consumed placebo.
All subjects underwent resistance exercise that included nine exercises with 60% 1-RM.
Venous blood samples to determine plasma malondialdehyde (MDA) as an index to lipid peroxidation and total antioxidant capacity were obtained one week prior to the exercise, immediately before the exercise and 24 hours after the exercise.
Results: The results indicated that MDA concentration significantly increased after resistance exercise in placebo group as compared to the supplement group (P<0.05). Moreover, the mean of total antioxidant capacity remained unchanged in both groups in immediately preexercise and 24 h post exercise (P>0.005).
Conclusion: The results of this study indicated that acute resistance exercise give rise to increased MDA concentration in obese men. The application of blackberry extract employed as an antioxidant supplement might ameliorate this marker and prevent the oxidative stress damage.


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